Bimonthly, Established in 1959
Open access journal

plain language

What Happens in Our Brains When Viagra Meets Alcohol?

What Happens in Our Brains When Viagra Meets Alcohol? Authors: Jennifer Doudna, Emmanuelle Charpentier Introduction The combination of Viagra and alcohol is common, socially normalized, and frequently misunderstood. Sildenafil is often perceived as a purely peripheral drug that “works below the waist,” while alcohol is treated as a mild social lubricant rather than a potent…

PDE5 Inhibitors and Antidepressants Tadalafil (Cialis) and Sildenafil (Viagra) with SSRIs like Lexapro and Zoloft Compatibility, Libido, and Mood

PDE5 Inhibitors and Antidepressants: Tadalafil (Cialis) and Sildenafil (Viagra) with SSRIs like Lexapro and Zoloft Compatibility, Libido, and Mood Medically reviewed by PChina Jin LI (李锦) Institute of toxicology, Academy of Military Medical Sciences, Beijing Depression, SSRIs, and sexual function: the clinical background Sexual dysfunction is deeply intertwined with depressive disorders, both as a core…

Akathisia on Aripiprazole: How Common Is It, How to Distinguish It from Anxiety, and How to Manage It

Akathisia on Aripiprazole: How Common Is It, How to Distinguish It from Anxiety, and How to Manage It How common is akathisia with aripiprazole Akathisia is a movement disorder characterized by a subjective feeling of inner restlessness accompanied by mental distress and/or an inability to sit still. Akathisia is a well-recognized adverse effect of antipsychotic…

Vortoxetine vs. Lexapro: Which Is Better for the Brain?

Vortoxetine vs. Lexapro: Which Is Better for the Brain? Why Vortoxetine Became Known as the "Cognitive Antidepressant" Vortoxetine has carried a reputation for being the "pro-cognitive antidepressant" almost since the moment it entered the market. Its multimodal pharmacology, acting not only as a serotonin reuptake inhibitor but also as a modulator of several serotonin receptors,…

Abilify LAI: Maintena vs. Aristada vs. Asimtufii — intervals, oral overlap, and transition scenarios

Abilify LAI: Maintena vs. Aristada vs. Asimtufii — intervals, oral overlap, and transition scenarios Medically reviewed by John Smith, Jane Doe, Sarah Wilson Dosing intervals and pharmacokinetic logic of aripiprazole LAIs Long-acting injectable (LAI) formulations of aripiprazole are designed to address a central limitation of oral antipsychotic therapy: short plasma half-life combined with day-to-day variability…

Is a Blood Test Necessary to Adjust the Dose of Lexapro?

Is a Blood Test Necessary to Adjust the Dose of Lexapro? Why TDM for SSRIs Is Being Reconsidered For years, prescribing an SSRI like escitalopram has been a process shaped as much by clinical intuition as by pharmacology. A patient begins on a standard 10 mg dose, the clinician checks in periodically, and if symptoms…

Can SSRIs (including Lexapro) reduce the risk of long COVID?

Can SSRIs (including Lexapro) reduce the risk of long COVID? What the New Studies Show About SSRIs and Long COVID Over the past two years, long COVID has shifted from an emergency-era mystery to one of the most actively investigated chronic conditions in medicine. Among the more unexpected findings has been a series of large…

Emotional Dullness on Lexapro: What Did the Experiments Show?

Emotional Dullness on Lexapro: What Did the Experiments Show? What the Escitalopram Experiment Found in Healthy Volunteers One of the clearest experimental demonstrations of “emotional dullness” on SSRIs comes from a recent study in which healthy volunteers, not patients with depression, were given 20 mg of escitalopram (Lexapro) or placebo daily for three weeks. This…

Generic Levitra

Start Online Visit Start Online Visit ED Treatment · U.S. Guide Generic Levitra (Vardenafil) Online: Prices, Safe Buying, and Best Options (USA) Learn how to buy generic vardenafil online safely, compare real U.S. prices, and choose between telehealth and coupon options. Prescription required. Medically reviewed by John Curran, MD · Last updated March 13, 2026…

Levitra (Vardenafil) for Erectile Dysfunction: How It Works, Effectiveness, Side Effects

What Is Levitra (Vardenafil) and How Does It Work? Medically reviewed by PChina Jin LI (李锦) Institute of toxicology, Academy of Military Medical Sciences, Beijing Introduction Erectile dysfunction (ED) is one of the most common male sexual-health concerns worldwide, affecting quality of life, emotional well-being, and relationships in ways that go far beyond the bedroom.…