Bimonthly, Established in 1959
Open access journal

Advancing Depression Treatment: Insights from Recent Research on Environmental Influences and Innovative Therapies

In recent research, the relationship between workplace stress, specifically effort-reward imbalance, and its influence on depressive disorders has been explored, highlighting environmental impacts on mental health. Additionally, systematic reviews have critically assessed various staging models for treatment-resistant depression, revealing the importance of accurate diagnosis and tailored treatment strategies. Non-pharmacological interventions in primary care, especially for older adults, demonstrate the effectiveness of alternatives to traditional medication, such as cognitive behavioral therapy. Furthermore, studies on the interplay between physical health and mental well-being suggest that weight loss interventions can indirectly alleviate symptoms of depression. Lastly, the effectiveness of diverse nonpharmacological treatments for older adults emphasizes the necessity for customized approaches in geriatric mental health care, underscoring the complexity and multidimensional nature of treating depression.

Effort-reward imbalance at work and risk of depressive disorders. A systematic review and meta-analysis of prospective cohort studies

Authors: Reiner Rugulies, Birgit Aust, Ida Eh Madsen

Summary: This systematic review and meta-analysis examine how imbalances between the efforts spent and rewards received at work contribute to the risk of developing depressive disorders. The study emphasizes the psychosocial stressor’s significant impact on mental health outcomes.


Staging methods for treatment resistant depression

Authors: Henricus G Ruhé, Geeske van Rooijen, Jan Spijker, Frenk P M L Peeters, Aart H Schene

Summary: This systematic review discusses various models used for staging treatment-resistant depression (TRD), including the Massachusetts General Hospital Staging model and the Maudsley Staging Model. It highlights the evolution and predictive utility of these models, suggesting improved staging can enhance the generalizability of clinical study results and patient care.


Non-pharmacological treatment for depressed older patients in primary care: A systematic review and meta-analysis

Authors: João Apóstolo, Paulo Queirós, Manuel Rodrigues, Inês Castro, Daniela Cardoso

Summary: This meta-analysis focuses on non-pharmacological interventions like cognitive-behavioral therapy for treating depression in older adults within primary care settings. The findings support the effectiveness of these interventions, providing a valuable alternative to medication.


Behavioral and Pharmacotherapy Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults

Authors: Erin L. LeBlanc, Carrie D. Patnode, Elizabeth M. Webber, Nadia Redmond, Megan Rushkin, Elizabeth A. O’Connor

Summary: Although not directly focused on depression, this systematic review addresses interventions that could indirectly improve depressive symptoms by targeting obesity-related health issues, which are often associated with poor mental health.