Bimonthly, Established in 1959
Open access journal

In This Issue:

Systematic Review and Meta-Analysis

Neuroimaging Techniques in the Diagnosis of Alzheimer’s Disease

Xiaoli HUANG, Ming ZHAO

Summary: Alzheimer’s disease (AD) presents significant diagnostic challenges, particularly in its early stages. This review consolidates findings from studies using advanced neuroimaging techniques, such as MRI and amyloid PET scans, which have shown potential in identifying early biomarkers of AD. While these techniques are promising, the review emphasizes their current status as part of ongoing research and their yet-to-be-established roles in routine clinical diagnosis.

Keywords: Alzheimer’s disease, neuroimaging, MRI, PET scans, biomarkers, early diagnosis

Original Research Article

Impact of Urbanization on Mental Health in Emerging Economies

Rajesh SINGH, Ananya DUTTA

Background: Rapid urbanization in emerging economies is often associated with increased stress and mental health disorders.

Aim: To examine the correlation between urbanization and the prevalence of mental health disorders in major urban versus rural settings in India.

Methods: A cross-sectional survey of 1,000 participants, with 500 from urban areas and 500 from rural settings, assessing levels of anxiety, depression, and stress using standardized psychological scales.

Results: Participants from urban areas exhibited higher levels of stress and anxiety compared to their rural counterparts, underscoring the potential mental health impacts of urban living.

Conclusion: These findings highlight the need for enhanced mental health services and interventions in urban areas of emerging economies.

Keywords: urbanization, mental health, emerging economies, stress, anxiety

Randomized Controlled Trial

Omega-3 Fatty Acids in the Treatment of Postpartum Depression

Li JIE, Wang TAO

Background: Postpartum depression is a significant concern affecting maternal health and family well-being.

Aim: To explore the potential benefits of omega-3 fatty acid supplementation in alleviating symptoms of postpartum depression.

Methods: This double-blind trial involved 90 postpartum women with mild to moderate depressive symptoms, randomized to receive either omega-3 supplements or a placebo for 12 weeks. Depression severity was measured using the Edinburgh Postnatal Depression Scale (EPDS).

Results: The omega-3 group showed a greater reduction in EPDS scores than the placebo group, suggesting some benefits.

Conclusion: While omega-3 supplements show promise in reducing postpartum depression symptoms, further studies are necessary to fully establish their efficacy and safety.

Keywords: postpartum depression, omega-3, randomized controlled trial, EPDS

Case Report

A Case of Neuroleptic Malignant Syndrome in a Patient with Bipolar Disorder

Chen WEI, Liu YANG

Summary: This case report describes a serious and rare occurrence of neuroleptic malignant syndrome (NMS) in a patient treated with antipsychotics for bipolar disorder, detailing the critical symptoms, emergency treatments, and the crucial need for rapid diagnosis and management of this life-threatening condition.

Keywords: neuroleptic malignant syndrome, bipolar disorder, antipsychotics, emergency treatment, case report

Biostatistics in Psychiatry

Analyzing Longitudinal Data in Psychiatric Research

Hong LI, Tao ZHENG

Summary: This paper discusses statistical methods for analyzing longitudinal psychiatric data, with a focus on mixed-effects models and time-to-event analysis. It provides examples from studies on the effectiveness of treatments for depression and schizophrenia, illustrating how these methods help understand changes over time and treatment effects.

Keywords: longitudinal data, biostatistics, psychiatric research, mixed-effects model, depression, schizophrenia


Global Mental Health: Challenges and Progress

Sanjay GUPTA, Jyoti VERMA

Discussion: This article examines global mental health challenges, with a specific focus on disparities in mental health services in low and middle-income countries. It reviews recent international efforts to address these challenges and improve global mental health care systems and policies.

Case Report

Unusual Presentation of Schizophrenia in an Elderly Patient


Summary: This case involves an 80-year-old male initially suspected of having dementia but later diagnosed with late-onset schizophrenia. The report underscores the importance of differential diagnosis in elderly patients presenting with psychiatric symptoms, particularly the need for careful assessment to distinguish between dementia and schizophrenia.

Keywords: late-onset schizophrenia, elderly, dementia, differential diagnosis, case report