Insights · Pain drug development After Journavx: What LTG-001 Changes for the Emerging NaV1.8 Drug Class Journavx made NaV1.8 inhibition a regulatory reality. A new Phase 2b trial now asks a more consequential question: are we watching one successful drug, or the beginning of a competitive analgesic class? Published August 17, 2026Phase 2b trial analysisAcute…

Tramadol for Dogs: Does It Still Work? Doses, Costs, and Caregiver Anxiety Answer in a nutshell: Evidence for tramadol in dogs is mixed; alternatives or combinations often work better. Always dose per veterinary guidance. Introduction For years, tramadol was one of the most common pain medications prescribed to dogs. Veterinarians and pet owners alike viewed…